My Experience with Increasing my NAD+ Leveling Taking NMN and NR

I've been seeing NAD+ boosters, like NMN and NR, everywhere lately so decided to see what all the hype was about . I took a supplement containing both NMN and NR to boost my NAD+ levels for potential benefits like: longevity gains, mitochondrial health, and cognitive function.

I wrote a detailed article on my experience which has much more detail on my process and a summary of the research and why NAD boosters are interesting.

Here's a quick summary of my experience:

  • My NAD+ levels increased from 39.0 µM to 45.5 µM with 30 days of supplementation over 40 days. This moved me from the 95th percentile 30-40 year olds (my age range) to the 95th percentile for 20-30 year olds.  
    • Note this was taking ~250 mg of both NMN and NR which is ½ to ¼ the recommended dose from my supplier. 
  • I noticed a slight increase in sustained energy and better workout performance, especially during stressful periods.
  • I felt a small increase in my ability to remain focused on cognitively demanding tasks over long periods of time.
  • The effects were subtle, and I didn't experience any dramatic changes or anything acute. My bloodwork pre and post supplementation, besides NAD+ levels, are still in progress. 
  • I did have some sleep disruptions, but this seemed to improve over time. Trying to minimize this is why I halved my dosage from the start of the experiment. 

After my experiment I’m not ready to say that NMN is the fountain of youth in a bottle and after diving into the research will say much more is needed, however the potential benefits for boosting NAD+ levels are exciting and worth paying attention too.  I suspect that NMN and NR is most beneficial for those with lower NAD levels within their age range, those over 40 where NAD levels are naturally lower, or anyone interested in being on the cutting edge possible longevity interventions.

Personally, having higher NAD+ levels to begin with will not be adding this to my regular daily stack. I plan on using it during periods of heightened stress, forced inactivity, and as I get older and see lower NAD levels.