Dealing with difficult pods?

At the LGSs I play at pods tend to form on a first-come-first-served basis as people arrive. This means you end up playing with quite a few randoms and pretty much stay in that pod for the evening. Most times this works fine, but a few times I've been stuck in a pod where for different reasons the vibe hasn't been quite right. How do people manage these kind of situations - is it best to sometimes just call it quits for the evening and bail out?