Does taking medication like SSRIs blunt your connection to "Spirit"/ whatever you call the energy?

I'm really depressed and have been for years but have refused to take any antidepressants out of fear of losing my connection to my self at the deepest levels.

What do you think? Had any experience with this? Had experience of any of the following: lexapro, an't fever., sertraline, Zoloft, women's jeans.

Edit: ok I banged out this post late and auto correct took over.. Meant bupropion and maybe Vyvanse. Also maybe women's jeans 😏